Connectivity and communication protocols

To transmit their input, typical cabled mice use a thin electrical cord terminating in a standard connector, such as RS-232C, PS/2, ADB orUSB. Cordless mice instead transmit data via infrared radiation (see IrDA) or radio (including Bluetooth), although many such cordless interfaces are themselves connected through the aforementioned wired serial buses.

While the electrical interface and the format of the data transmitted by commonly available mice is currently standardized on USB, in the past it varied between different manufacturers. A bus mouse used a dedicated interface card for connection to an IBM PC or compatible computer.

Mouse use in DOS applications became more common after the introduction of the Microsoft mouse, largely because Microsoft provided an open standard for communication between applications and mouse driver software. Thus, any application written to use the Microsoft standard could use a mouse with a Microsoft compatible driver (even if the mouse hardware itself was incompatible with Microsoft's). An interesting footnote is that the Microsoft driver standard communicates mouse movements in standard units called "mickeys".